Two mechanisms drive pronuclear migration in mouse zygotes

In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear. Here, the authors report that both F-actin and microtubule polymerization act in concern to drive inward movement of pronuclei toward...

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Bibliographic Details
Main Authors: Kathleen Scheffler, Julia Uraji, Ida Jentoft, Tommaso Cavazza, Eike Mönnich, Binyam Mogessie, Melina Schuh
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21020-x