Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flow.

A non-receptor protein kinase Src plays a crucial role in fundamental cell functions such as proliferation, migration, and differentiation. While inhibition of Src is reported to contribute to chondrocyte homeostasis, its regulation at a subcellular level by chemical inhibitors and mechanical stimul...

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Bibliographic Details
Main Authors: Qiaoqiao Wan, Wenxiao Xu, Jing-long Yan, Hiroki Yokota, Sungsoo Na
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4144888?pdf=render