Nonlinearity arising from noncooperative transcription factor binding enhances negative feedback and promotes genetic oscillations
We study the effects of multiple binding sites in the promoter of a genetic oscillator. We evaluate the regulatory function of a promoter with multiple binding sites in the absence of cooperative binding, and consider different hypotheses for how the number of bound repressors affects transcription...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Papers in Physics
2014-11-01
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| Series: | Papers in Physics |
| Subjects: | |
| Online Access: | http://www.papersinphysics.org/index.php/papersinphysics/article/view/206/pdf206 |