The Dynactin Complex Enhances the Speed of Microtubule-Dependent Motions of Adenovirus Both Towards and Away from the Nucleus

The Dynactin Complex Enhances the Speed of Microtubule-Dependent Motions of Adenovirus Both Towards and Away from the Nucleus

Unlike transport vesicles or organelles, human adenovirus (HAdV) directly binds to the microtubule minus end-directed motor dynein for transport to the nucleus. The dynein cofactor dynactin enhances nuclear transport of HAdV and boosts infection. To determine if dynactin has a specific role in cytop...

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Bibliographic Details
Main Authors: Martin F. Engelke, Christoph J. Burckhardt, Urs F. Greber, Matthias K. Morf
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Viruses
Subjects:
dynein
motor
cytoplasmic transport
cytoskeleton
virus motion
infection
Online Access:http://www.mdpi.com/1999-4915/3/3/233/

Internet

http://www.mdpi.com/1999-4915/3/3/233/

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