Microfibrillar-associated protein 5 regulates osteogenic differentiation by modulating the Wnt/β-catenin and AMPK signaling pathways

Microfibrillar-associated protein 5 regulates osteogenic differentiation by modulating the Wnt/β-catenin and AMPK signaling pathways

Abstract Background Dysfunctional osteogenesis of bone marrow mesenchymal stem cells (BMSCs) plays an important role in osteoporosis occurrence and development. However, the molecular mechanisms of osteogenic differentiation remain unclear. This study explored whether microfibrillar-associated prote...

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Bibliographic Details
Main Authors: Haoran Li, Wuling Zhou, Shiwei Sun, Tianlong Zhang, Tieqi Zhang, Haitian Huang, Minghai Wang
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Molecular Medicine
Subjects:
Bone marrow mesenchymal stem cells (BMSCs)
MFAP5
Osteoporosis
Osteogenesis
Wnt/β-catenin
AMPK
Online Access:https://doi.org/10.1186/s10020-021-00413-0

Internet

https://doi.org/10.1186/s10020-021-00413-0

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