Antileishmanial activity of lapachol analogues

The antileishmanial activity of lapachol, isolapachol, and dihydrolapachol, along with soluble derivatives (potassium salt) and acetate was obtained. All the compounds were assayed against metacyclic promastigotes of two different species of Leishmania associated to tegumentar leishmaniasis: L. amaz...

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Bibliographic Details
Main Authors: Nadja MF Lima, Clariane S Correia, Leonor L Leon, Gérzia MC Machado, Maria de Fátima Madeira, Antônio Euzébio G Santana, Marília OF Goulart
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2004-11-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000700017