THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets.

THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets.

Fc gamma receptors (FcγRs) are critical effector receptors for immunoglobulin G (IgG) antibodies. On macrophages, FcγRs mediate multiple effector functions, including phagocytosis, but the individual contribution of specific FcγRs to phagocytosis has not been fully characterized. Primary human macro...

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Bibliographic Details
Main Authors: Lazaro Gil Gonzalez, Yuniel Fernandez-Marrero, Peter Alan Albert Norris, Zoya Tawhidi, Yuexin Shan, Yoelys Cruz-Leal, Kevin Doyoon Won, Kayluz Frias-Boligan, Donald R Branch, Alan H Lazarus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0278365

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https://doi.org/10.1371/journal.pone.0278365

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