Efficient Tandem Addition/Cyclization for Access to 2,4-Diarylquinazolines via Catalytic Carbopalladation of Nitriles

Efficient Tandem Addition/Cyclization for Access to 2,4-Diarylquinazolines via Catalytic Carbopalladation of Nitriles

The first example of the palladium-catalyzed tandem addition/cyclization of 2-(benzylidenamino)benzonitriles with arylboronic acids has been developed. This transformation features good functional group tolerance and provides an alternative synthetic pathway to access 2,4-diarylquinazolines in moder...

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Bibliographic Details
Main Authors: Julin Gong, Kun Hu, Yetong Zhang, Yinlin Shao, Tianxing Cheng, Maolin Hu, Jiuxi Chen
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
palladium-catalyzed
tandem reaction
nitrile
carbopalladation
quinazoline
Online Access:https://www.mdpi.com/1420-3049/24/3/463

Internet

https://www.mdpi.com/1420-3049/24/3/463

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