Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions

Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions

Rett syndrome (RTT) and Fragile X syndrome (FXS) are two monogenetic neurodevelopmental disorders with complex clinical presentations. RTT is caused by mutations in the Methyl-CpG binding protein 2 gene (MECP2) altering the function of its protein product MeCP2. MeCP2 modulates gene expression by bi...

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Bibliographic Details
Main Authors: Snow Bach, Stephen Shovlin, Michael Moriarty, Barbara Bardoni, Daniela Tropea
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Rett syndrome
Fragile X syndrome
synaptic plasticity
FMRP
MeCP2
neurodevelopmental disorders
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.764761/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.764761/full

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