Active H3K27me3 demethylation by KDM6B is required for normal development of bovine preimplantation embryos
The substantial epigenetic remodeling that occurs during early stages of mammalian embryonic development likely contributes to reprogramming the parental genomes from a differentiated to a totipotent state and activation of the embryonic genome. Trimethylation of lysine 27 of histone 3 (H3K27me3) is...
Main Authors: | , , , , , , , |
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格式: | Article |
語言: | English |
出版: |
Taylor & Francis Group
2017-12-01
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叢編: | Epigenetics |
主題: | |
在線閱讀: | http://dx.doi.org/10.1080/15592294.2017.1403693 |