Active H3K27me3 demethylation by KDM6B is required for normal development of bovine preimplantation embryos

The substantial epigenetic remodeling that occurs during early stages of mammalian embryonic development likely contributes to reprogramming the parental genomes from a differentiated to a totipotent state and activation of the embryonic genome. Trimethylation of lysine 27 of histone 3 (H3K27me3) is...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Nhi Chung, Yanina S. Bogliotti, Wei Ding, Marcela Vilarino, Kazuki Takahashi, James L. Chitwood, Richard M. Schultz, Pablo J. Ross
التنسيق: مقال
اللغة:English
منشور في: Taylor & Francis Group 2017-12-01
سلاسل:Epigenetics
الموضوعات:
الوصول للمادة أونلاين:http://dx.doi.org/10.1080/15592294.2017.1403693