Down-Regulation of Tim-3 in Monocytes and Macrophages in Plasmodium Infection and Its Association with Parasite Clearance

Down-Regulation of Tim-3 in Monocytes and Macrophages in Plasmodium Infection and Its Association with Parasite Clearance

T-cell immunoglobulin and mucin-domain-containing molecule 3 (Tim-3) has complicated roles in regulating monocytes and macrophages in various diseases and it tends to be an inhibitory molecule to facilitate the immune escape of parasites in malaria. However, the mechanisms of Tim-3 mediated response...

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Bibliographic Details
Main Authors: Nan Hou, Ning Jiang, Yang Zou, Xianyu Piao, Shuai Liu, Shanshan Li, Qijun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
malaria
Tim-3
monocytes
macrophages
Plasmodium
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01431/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01431/full

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