Heparan Sulfate Proteoglycan: An Arbovirus Attachment Factor Integral to Mosquito Salivary Gland Ducts

Heparan Sulfate Proteoglycan: An Arbovirus Attachment Factor Integral to Mosquito Salivary Gland Ducts

Variants of the prototype Alphavirus, Sindbis (SINV), were used in per os infections of adult female mosquitoes to investigate arbovirus interaction with the salivary gland (SG). Infection of Aedine mosquitoes with AR339, a heparan sulfate proteoglycan (HSPG)-dependent variant, resulted in gross pat...

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Bibliographic Details
Main Authors: Kristen A. Ciano, Jason J. Saredy, Doria F. Bowers
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Viruses
Subjects:
Alphavirus
heparan sulfate proteoglycan
Aedine mosquitoes
salivary gland ducts
Sindbis virus
GFP
Online Access:http://www.mdpi.com/1999-4915/6/12/5182

Internet

http://www.mdpi.com/1999-4915/6/12/5182

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