Virtual Screening, Synthesis, and Biological Evaluation of Some Carbohydrazide Derivatives as Potential DPP-IV Inhibitors

Virtual Screening, Synthesis, and Biological Evaluation of Some Carbohydrazide Derivatives as Potential DPP-IV Inhibitors

Dipeptidyl peptidase-4 (DPP-IV) inhibitors are known as safe and well-tolerated antidiabetic medicine. Therefore, the aim of the present work was to synthesize some carbohydrazide derivatives (<b>1a</b>–<b>5d</b>) as DPP-IV inhibitors. In addition, this work involves simulati...

Full description

Bibliographic Details
Main Authors: Prerana B. Jadhav, Shailaja B. Jadhav, Mehrukh Zehravi, Mohammad S. Mubarak, Fahadul Islam, Philippe Jeandet, Sharuk L. Khan, Nazmul Hossain, Salma Rashid, Long Chiau Ming, Md. Moklesur Rahman Sarker, Mohd Fahami Nur Azlina
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
DPP-IV
in vivo
carbohydrazide
2P8S
ADMET
molecular docking
Online Access:https://www.mdpi.com/1420-3049/28/1/149

Internet

https://www.mdpi.com/1420-3049/28/1/149

Similar Items