Improved Pathologic response to chemoradiation in MGMT methylated locally advanced rectal cancer

Improved Pathologic response to chemoradiation in MGMT methylated locally advanced rectal cancer

Background and Purpose: With the growing interest in total neoadjuvant treatment for locally advanced rectal adenocarcinoma (LARC) there is an urgent unmet need to identify predictive markers of response to long-course neoadjuvant concurrent chemoradiotherapy (LCRT). O6-Methylguanine (O6-MG)-DNA-met...

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Bibliographic Details
Main Authors: Garrett L. Jensen, Niloufar Pourfarrokh, Marcus Volz, Linden L. Morales, Kimberly Walker, Kendall P. Hammonds, Moataz El-Ghamry, Lucas Wong, Parsa Hodjat, Eduardo Castro, Arundhati Rao, Sameer G. Jhavar
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Clinical and Translational Radiation Oncology
Subjects:
MGMT
Alkylating
Chemosensitive
Methylation
Radiosensitive
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630823000927

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http://www.sciencedirect.com/science/article/pii/S2405630823000927

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