Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis

Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis

Abstract Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a prototypic autoimmune disease, with a subset of AAV patients manifesting anti-myeloperoxidase (MPO) IgG. Patients with AAV respond positively to B cell-targeting and complement-targeting therapies, but disease flar...

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Bibliographic Details
Main Authors: CM Wortel, R. van de Wetering, EM Stork, T. Kissel, S. Reijm, D. van der Woude, KA van Schie, LA Trouw, YKO Teng, A. Rutgers, P. Heeringa, RE Voll, M. Rizzi, N. Venhoff, REM Toes, HU Scherer
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56786-x

Internet

https://doi.org/10.1038/s41467-025-56786-x

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