Development of Phosphorothioate DNA and DNA Thioaptamers

Nucleic acid aptamers are short RNA- or DNA-based affinity reagents typically selected from combinatorial libraries to bind to a specific target such as a protein, a small molecule, whole cells or even animals. Aptamers have utility in the development of diagnostic, imaging and therapeutic applicati...

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Bibliographic Details
Main Authors: David E. Volk, Ganesh L. R. Lokesh
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/5/3/41