The Matrix-M™ adjuvant: A critical component of vaccines for the 21st century

The Matrix-M™ adjuvant: A critical component of vaccines for the 21st century

Matrix-M™ adjuvant is a key component of several novel vaccine candidates. The Matrix-M adjuvant consists of two distinct fractions of saponins purified from the Quillaja saponaria Molina tree, combined with cholesterol and phospholipids to form 40-nm open cage-like nanoparticles, achieving potent a...

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Bibliographic Details
Main Authors: Linda Stertman, Anna-Karin E. Palm, Behdad Zarnegar, Berit Carow, Carolina Lunderius Andersson, Sofia E. Magnusson, Cecilia Carnrot, Vivek Shinde, Gale Smith, Gregory Glenn, Louis Fries, Karin Lövgren Bengtsson
Format: Article
Language:English
Published: Taylor & Francis Group 2023-01-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
matrix-m™ adjuvant
quillaja saponin
vaccine
immunogenicity
safety
mechanism of action
innate immune response
adaptive immune response
sars-cov-2
covid-19
Online Access:http://dx.doi.org/10.1080/21645515.2023.2189885

Internet

http://dx.doi.org/10.1080/21645515.2023.2189885

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