Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Abstract Nutrient availability is the major regulator of life and reproduction, and a complex cellular signaling network has evolved to adapt organisms to fasting. These sensor pathways monitor cellular energy metabolism, especially mitochondrial ATP production and NAD+/NADH ratio, as major signals...

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Bibliographic Details
Main Authors: Nahid A Khan, Mari Auranen, Ilse Paetau, Eija Pirinen, Liliya Euro, Saara Forsström, Lotta Pasila, Vidya Velagapudi, Christopher J Carroll, Johan Auwerx, Anu Suomalainen
Format: Article
Language:English
Published: Springer Nature 2014-04-01
Series:EMBO Molecular Medicine
Subjects:
mitochondrial myopathy
NAD+
nicotinamide riboside
treatment
unfolded protein response
Online Access:https://doi.org/10.1002/emmm.201403943

Internet

https://doi.org/10.1002/emmm.201403943

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