Microcarrier-Expanded Neural Progenitor Cells Can Survive, Differentiate, and Innervate Host Neurons Better When Transplanted as Aggregates

Neuronal progenitor cells (NPCs) derived from human embryonic stem cells (hESCs) are an excellent cell source for transplantation therapy due to their availability and ethical acceptability. However, the traditional method of expansion and differentiation of hESCs into NPCs in monolayer cultures req...

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Bibliographic Details
Main Authors: Lifeng Qiu, Yu Ming Lim, Allen K. Chen, Shaul Reuveny, Steve K. W. Oh, Eng King Tan, Li Zeng
Format: Article
Language:English
Published: SAGE Publishing 2016-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X690378