The Abnormal CD4+T Lymphocyte Subset Distribution and Vbeta Repertoire in New-onset Rheumatoid Arthritis Can Be Modulated by Methotrexate Treament

The Abnormal CD4+T Lymphocyte Subset Distribution and Vbeta Repertoire in New-onset Rheumatoid Arthritis Can Be Modulated by Methotrexate Treament

Patients with long-term, treated, rheumatoid arthritis (RA) show abnormalities in their circulating CD4+ T-lymphocytes, but whether this occurs in recently diagnosed naïve patients to disease-modifying drugs (DMARDs) is under discussion. These patients show heterogeneous clinical response t...

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Bibliographic Details
Main Authors: Jorge Monserrat, Cristina Bohórquez, Ana María Gómez Lahoz, Atusa Movasat, Ana Pérez, Lucía Ruíz, David Díaz, Luis Chara, Ana Isabel Sánchez, Fernando Albarrán, Ignacio Sanz, Melchor Álvarez-Mon
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
rheumatoid arthritis
CD4+ T lymphocytes
methotrexate
flow cytometry
TCR Vb
Online Access:https://www.mdpi.com/2073-4409/8/8/871

Internet

https://www.mdpi.com/2073-4409/8/8/871

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