Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats

Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats

Abstract Although systolic function characteristically shows gradual impairment in pressure overload (PO)-evoked left ventricular (LV) hypertrophy (LVH), rapid progression to congestive heart failure (HF) occurs in distinct cases. The molecular mechanisms for the differences in maladaptation are unk...

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Bibliographic Details
Main Authors: Mihály Ruppert, Sevil Korkmaz-Icöz, Bettina Benczik, Bence Ágg, Dávid Nagy, Tímea Bálint, Alex Ali Sayour, Attila Oláh, Bálint András Barta, Kálmán Benke, Péter Ferdinandy, Matthias Karck, Béla Merkely, Tamás Radovits, Gábor Szabó
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43171-1

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https://doi.org/10.1038/s41598-023-43171-1

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