Dexmedetomidine enables copper homeostasis in cerebral ischemia/reperfusion via ferredoxin 1

AbstractExcessive oxygen free radicals and toxic substances are generated in cerebral ischemia-reperfusion (I/R) process. Dexmedetomidine (DEX), a common anesthetic and sedative drug, can considerably boost glutathione (GSH), which has anti-copper influx effects. Focusing on cuproptosis, the mechani...

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Bibliographic Details
Main Authors: Qingduo Guo, Meina Ma, Hong Yu, Yuepeng Han, Dong Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Annals of Medicine
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2023.2209735