Follistatin-Like 1 Promotes Bleomycin-Induced Pulmonary Fibrosis through the Transforming Growth Factor Beta 1/Mitogen-Activated Protein Kinase Signaling Pathway

Follistatin-Like 1 Promotes Bleomycin-Induced Pulmonary Fibrosis through the Transforming Growth Factor Beta 1/Mitogen-Activated Protein Kinase Signaling Pathway

Background: Follistatin-like 1 (FSTL1) is a novel profibrogenic factor that induces pulmonary fibrosis (PF) through the transforming growth factor-beta 1 (TGF-β1)/Smad signaling. Little is known about its effects on PF through the non-Smad signaling, like the mitogen-activated protein kinase (MAPK)...

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Bibliographic Details
Main Authors: Yan-Kun Jin, Xiao-He Li, Wang Wang, Jie Liu, Wei Zhang, Yin-Shan Fang, Zhi-Fei Zhang, Hua-Ping Dai, Wen Ning, Chen Wang
Format: Article
Language:English
Published: Wolters Kluwer 2018-01-01
Series:Chinese Medical Journal
Subjects:
Follistatin-Like 1; Mitogen-Activated Protein Kinase; Pulmonary Fibrosis; Transforming Growth Factor Beta 1
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=16;spage=1917;epage=1925;aulast=Jin

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http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=16;spage=1917;epage=1925;aulast=Jin

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