Emerging Role of C5 Complement Pathway in Peripheral Neuropathies: Current Treatments and Future Perspectives

Emerging Role of C5 Complement Pathway in Peripheral Neuropathies: Current Treatments and Future Perspectives

The complement system is a key component of innate immunity since it plays a critical role in inflammation and defense against common pathogens. However, an inappropriate activation of the complement system is involved in numerous disorders, including peripheral neuropathies. Current strategies for...

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Bibliographic Details
Main Authors: Cristina Giorgio, Mara Zippoli, Pasquale Cocchiaro, Vanessa Castelli, Giustino Varrassi, Andrea Aramini, Marcello Allegretti, Laura Brandolini, Maria Candida Cesta
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
complement system
C5a/C5aR axis
C5a receptor1
peripheral neuropathy
pain
C5aR inhibitor
Online Access:https://www.mdpi.com/2227-9059/9/4/399

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https://www.mdpi.com/2227-9059/9/4/399

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