A protective role of HTLV-1 gp46-specific neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies in progression to adult T-cell leukemia (ATL)

A protective role of HTLV-1 gp46-specific neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies in progression to adult T-cell leukemia (ATL)

Human T-cell leukemia virus type-1 (HTLV-1) establishes a long-term persistent infection in humans and causes malignant T-cell leukemia, adult T-cell leukemia (ATL). HTLV-1-specific cytotoxic T lymphocytes have been suggested to play a major role in the immunosurveillance of HTLV-1-infected T cells....

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Bibliographic Details
Main Authors: Yuetsu Tanaka, Reiko Tanaka, Naoki Imaizumi, Mariko Mizuguchi, Yoshiaki Takahashi, Masaki Hayashi, Takashi Miyagi, Junnosuke Uchihara, Kazuiku Ohshiro, Hiroaki Masuzaki, Takuya Fukushima
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
ATL
HTLV-1
antibody
neutralization
ADCC
gp46
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.921606/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.921606/full

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