Cytoplasmic delivery of siRNA using human-derived membrane penetration-enhancing peptide
Abstract Background Although protein-based methods using cell-penetrating peptides such as TAT have been expected to provide an alternative approach to siRNA delivery, the low efficiency of endosomal escape of siRNA/protein complexes taken up into cells by endocytosis remains a problem. Here, to ove...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-10-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12951-022-01667-4 |