IL-1 and senescence: Friends and foe of EGFR neutralization and immunotherapy

Historically, senescence has been considered a safe program in response to multiple stresses in which cells undergo irreversible growth arrest. This process is characterized by morphological and metabolic changes, heterochromatin formation, and secretion of inflammatory components, known as senescen...

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Bibliographic Details
Main Authors: Donatella Romaniello, Valerio Gelfo, Federica Pagano, Michela Sgarzi, Alessandra Morselli, Cinzia Girone, Daria Maria Filippini, Gabriele D’Uva, Mattia Lauriola
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1083743/full