FAP, CD10, and GPR77-labeled CAFs cause neoadjuvant chemotherapy resistance by inducing EMT and CSC in gastric cancer

Abstract Objective A significant proportion of patients can not benefit from neoadjuvant chemotherapy (NCT) due to drug resistance. Cancer-associated fibroblasts (CAFs) influence many biological behaviours of tumors, including chemo-resistance. This study aims to explore whether CAFs expressing FAP,...

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Bibliographic Details
Main Authors: Zehua Zhao, Yanmei Zhu
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-11011-0