PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation

PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation

Abstract Background Myocardial ischemia-reperfusion injury (IRI) has become one of the most serious complications after reperfusion therapy in patients with acute myocardial infarction. Small ubiquitin-like modification (SUMOylation) is a reversible process, including SUMO E1-, E2-, and E3-mediated...

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Bibliographic Details
Main Authors: Bo Xie, Xinyu Liu, Jie Yang, Jinke Cheng, Jianmin Gu, Song Xue
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cell Biology
Subjects:
Ischemia-reperfusion injury
PIAS1
SUMOylation
PPARγ
NF-κB
Online Access:http://link.springer.com/article/10.1186/s12860-018-0176-x

Internet

http://link.springer.com/article/10.1186/s12860-018-0176-x

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