Optimization of HLA-B*27 ALLELE Genotyping by PCR-SSP

Optimization of HLA-B*27 ALLELE Genotyping by PCR-SSP

OBJECTIVES: HLA-B27 is strongly associated with ankylosing spondylitis (AS) and its presence helps to confirm AS diagnosis. Due to the high HLA polymorphism and the differentiated contribution of alleles and molecules encoded by them, HLA-B*27 allele identification is relevant in the clinical follow...

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Bibliographic Details
Main Authors: Fernanda Formaggi Lara-Armi, Jeane Eliete Laguila Visentainer, Hugo Vicentin Alves, Marco Antônio Rocha-Loures, Janisleya Silva Ferreira Neves, Cristiane Maria Colli, Quirino Alves de Lima Neto, Ricardo Alberto Moliterno, Ana Maria Sell
Format: Article
Language:English
Published: Elsevier España 2020-10-01
Series:Clinics
Subjects:
Spondyloarthropathies
Ankylosing Spondylitis
HLA-B27 Antigen
Polymerase Chain Reaction
Genotyping Techniques
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100286&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100286&tlng=en

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