Aptamer-functionalized chitosan-coated gold nanoparticle complex as a suitable targeted drug carrier for improved breast cancer treatment

In the following research, we specifically assessed the feasibility of a novel AS-1411-chitosan (CS)-gold nanoparticle (AuNPs) delivery system to carry methotrexate (MTX) into the cancer cells. The designed system had a spherical shape with average size of 62 ± 2.4 nm, the zeta potential of −32.1 ±...

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Bibliographic Details
Main Authors: Shahidi Maryamsadat, Abazari Omid, Dayati Parisa, Bakhshi Ali, Rasti Azam, Haghiralsadat Fateme, Naghib Seyed Morteza, Tofighi Davood
Format: Article
Language:English
Published: De Gruyter 2022-10-01
Series:Nanotechnology Reviews
Subjects:
Online Access:https://doi.org/10.1515/ntrev-2022-0479