Connectome and regulatory hubs of CAGE highly active enhancers

Abstract Evidence indicates that enhancers are transcriptionally active. Herein, we investigated transcriptionally active enhancers by using cap analysis of gene expression (CAGE) combined with epigenetic marks and chromatin interactions. We identified CAGE-tag highly active (CHA) enhancers as dista...

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Bibliographic Details
Main Authors: Mewen Briend, Anne Rufiange, Louis-Hippolyte Minvielle Moncla, Samuel Mathieu, Yohan Bossé, Patrick Mathieu
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32669-3