Major Surgical Trauma Impairs the Function of Natural Killer Cells but Does Not Affect Monocyte Cytokine Synthesis

Major Surgical Trauma Impairs the Function of Natural Killer Cells but Does Not Affect Monocyte Cytokine Synthesis

Major traumatic and surgical injury increase the risk for infectious complications due to immune dysregulation. Upon stimulation with interleukin (IL) 12 by monocyte/macrophages, natural killer (NK) cells release interferon (IFN) γ that supports the elimination of the pathogen. In the present study,...

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Bibliographic Details
Main Authors: Roman M. Müller-Heck, Björn Bösken, Ivo Michiels, Marcel Dudda, Marcus Jäger, Stefanie B. Flohé
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Life
Subjects:
surgery
trauma
injury
immune dysregulation
infection
natural killer cells
Online Access:https://www.mdpi.com/2075-1729/12/1/13

Internet

https://www.mdpi.com/2075-1729/12/1/13

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