CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation

Abstract Background Osteosarcoma (OS) is the most common malignant bone tumor with a high incidence in children and adolescents. Frequent tumor metastasis and high postoperative recurrence are the most common challenges in OS. However, detailed mechanism is largely unknown. Methods We examined the e...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Shiqi Lu, Tong Lu, Jiayu Zhang, Lunbiao Gan, Xinjie Wu, Donghui Han, Keying Zhang, Chao Xu, Shaojie Liu, Weijun Qin, Fa Yang, Weihong Wen
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: BMC 2023-03-01
Цуврал:BMC Cancer
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1186/s12885-023-10731-7