CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation
Abstract Background Osteosarcoma (OS) is the most common malignant bone tumor with a high incidence in children and adolescents. Frequent tumor metastasis and high postoperative recurrence are the most common challenges in OS. However, detailed mechanism is largely unknown. Methods We examined the e...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
BMC
2023-03-01
|
| סדרה: | BMC Cancer |
| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1186/s12885-023-10731-7 |