Map2k5-Deficient Mice Manifest Phenotypes and Pathological Changes of Dopamine Deficiency in the Central Nervous System

MAP2K5, a member of the MAPK family, is associated with central nervous system disorders. However, neural functional of Map2k5 from animal models were not well examined so far. Here, we established a Map2k5-targeted knockout mouse model to investigate the behavior phenotypes and its underlying molec...

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Bibliographic Details
Main Authors: Yumeng Huang, Pei Wang, Rodrigo Morales, Qi Luo, Jianfang Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.651638/full