Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes

Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes

Objective: Exposure of adipocytes to ‘cool’ temperatures often found in the periphery of the body induces expression of Stearoyl-CoA Desaturase-1 (Scd1), an enzyme that converts saturated fatty acids to monounsaturated fatty acids. The goal of this study is to further investigate the roles of Scd in...

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Bibliographic Details
Main Authors: Hiroyuki Mori, Sydney K. Peterson, Rachel C. Simmermon, Katherine A. Overmyer, Akira Nishii, Emma Paulsson, Ziru Li, Annie Jen, Romina M. Uranga, Jessica N. Maung, Warren T. Yacawych, Kenneth T. Lewis, Rebecca L. Schill, Taryn Hetrick, Ryo Seino, Ken Inoki, Joshua J. Coon, Ormond A. MacDougald
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Molecular Metabolism
Subjects:
Scd1
Stearoyl CoA Desaturase 1
ADCD
Autophagy-dependent cell death
BMAT
Bone marrow adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824000474

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http://www.sciencedirect.com/science/article/pii/S2212877824000474

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