Pituitary Adenylate Cyclase-Activating Polypeptide Protects Corneal Epithelial Cells against UV-B-Induced Apoptosis via ROS/JNK Pathway Inhibition

Pituitary Adenylate Cyclase-Activating Polypeptide Protects Corneal Epithelial Cells against UV-B-Induced Apoptosis via ROS/JNK Pathway Inhibition

PACAP is widely expressed throughout the body. It exerts a beneficial role in the eye, including the cornea. The corneal epithelium is regularly exposed to diverse types of insults, including ultraviolet B (UV-B) radiation. Previously, we showed the protective role played by PACAP in counteracting U...

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Bibliographic Details
Main Authors: Grazia Maugeri, Agata Grazia D’Amico, Benedetta Magrì, Elisabetta Pricoco, Cesarina Giallongo, Giuseppe Musumeci, Claudio Bucolo, Salvatore Giunta, Velia D’Agata
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Applied Sciences
Subjects:
cornea
UV-B
PACAP
ROS
apoptosis
JNK
Online Access:https://www.mdpi.com/2076-3417/12/7/3435

Internet

https://www.mdpi.com/2076-3417/12/7/3435

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