Ovarian carcinoma glyco-antigen targeted by human IgM antibody.

Ovarian carcinoma glyco-antigen targeted by human IgM antibody.

Epithelial Ovarian Cancer (EOC) cells expression of a novel carbohydrate antigen was defined using a human VH4-34 encoded IgM monoclonal antibody (mAb216). MAb216 binds to a poly N-acetyllactosamine epitope expressed on B cells and kills normal and malignant B cells in vitro and in vivo. EOC patient...

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Bibliographic Details
Main Authors: Yi Chen, Marcia M Bieber, Neelima M Bhat, Nelson N H Teng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739388?pdf=render

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http://europepmc.org/articles/PMC5739388?pdf=render

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