Multiple pkd and piezo gene family members are required for atrioventricular valve formation

Cardiac valves are essential for heart function, and blood flow stimulation is critical for their formation. Here, researchers have identified a set of mechanosensory genes of the pkd and piezo families as key regulators of valve development.

Bibliographic Details
Main Authors: Thomas Juan, Agatha Ribeiro da Silva, Bárbara Cardoso, SoEun Lim, Violette Charteau, Didier Y. R. Stainier
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35843-3