Context-dependent deposition and regulation of mRNAs in P-bodies

Context-dependent deposition and regulation of mRNAs in P-bodies

Cells respond to stress by remodeling their transcriptome through transcription and degradation. Xrn1p-dependent degradation in P-bodies is the most prevalent decay pathway, yet, P-bodies may facilitate not only decay, but also act as a storage compartment. However, which and how mRNAs are selected...

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Bibliographic Details
Main Authors: Congwei Wang, Fabian Schmich, Sumana Srivatsa, Julie Weidner, Niko Beerenwinkel, Anne Spang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
mRNA sorting
processing bodies
stress response
mRNA decay
lifespan
Online Access:https://elifesciences.org/articles/29815

Internet

https://elifesciences.org/articles/29815

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