Genome-wide linkage scan of a pedigree with familial hypercholesterolemia suggests susceptibility loci on chromosomes 3q25-26 and 21q22.

BACKGROUND: Familial hypercholesterolemia (FH) is a heritable disorder that can increase the risk of premature coronary heart disease. Studies suggest there are substantial genetic heterogeneities for different populations. Here we tried to identify novel susceptibility loci for FH in a Chinese pedi...

Full description

Bibliographic Details
Main Authors: Xu Wang, Xin Li, Yong-Biao Zhang, Feng Zhang, Liyuan Sun, Jie Lin, Duen-Mei Wang, Lu-Ya Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3194805?pdf=render