Brain structural correlates of recurrence following the first episode in patients with major depressive disorder

Abstract Former prospective studies showed that the occurrence of relapse in Major Depressive Disorder (MDD) is associated with volume loss in the insula, hippocampus and dorsolateral prefrontal cortex (DLPFC). However, these studies were confounded by the patient’s lifetime disease history, as the...

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Bibliographic Details
Main Authors: Hannah Lemke, Hannah Klute, Jennifer Skupski, Katharina Thiel, Lena Waltemate, Alexandra Winter, Fabian Breuer, Susanne Meinert, Melissa Klug, Verena Enneking, Nils R. Winter, Dominik Grotegerd, Elisabeth J. Leehr, Jonathan Repple, Katharina Dohm, Nils Opel, Frederike Stein, Tina Meller, Katharina Brosch, Kai G. Ringwald, Julia-Katharina Pfarr, Florian Thomas-Odenthal, Tim Hahn, Axel Krug, Andreas Jansen, Walter Heindel, Igor Nenadić, Tilo Kircher, Udo Dannlowski
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02113-7