Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing

The stereoselective analysis of mixtures of chiral compounds typically requires time-consuming chromatography. Here, the authors combine reaction based chiroptical sensing and chemometric tools to directly determine the absolute configuration, enantiomeric composition and concentration of convoluted...

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Bibliographic Details
Main Authors: Diandra S. Hassan, Christian Wolf
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26874-9