Loss of mDia1 and Fhod1 impacts platelet formation but not platelet function

An organized and dynamic cytoskeleton is required for platelet formation and function. Formins are a large family of actin regulatory proteins which are also able to regulate microtubule dynamics. There are four formin family members expressed in human and mouse megakaryocytes and platelets. We have...

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Bibliographic Details
Main Authors: Malou Zuidscherwoude, Elizabeth J. Haining, Victoria A. Simms, Stephanie Watson, Beata Grygielska, Alex T. Hardy, Andrea Bacon, Stephen P. Watson, Steven G. Thomas
Format: Article
Language:English
Published: Taylor & Francis Group 2021-11-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2020.1822522