T-Cell Subpopulations Exhibit Distinct Recruitment Potential, Immunoregulatory Profile and Functional Characteristics in Chagas versus Idiopathic Dilated Cardiomyopathies

Chronic Chagas cardiomyopathy (CCC) is one of the deadliest cardiomyopathies known and the most severe manifestation of Chagas disease, which is caused by infection with the parasite Trypanosoma cruzi. Idiopathic dilated cardiomyopathies (IDC) are a diverse group of inflammatory heart diseases that...

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Main Authors: Eula G. A. Neves, Carolina C. Koh, Thaiany G. Souza-Silva, Lívia Silva Araújo Passos, Ana Carolina C. Silva, Teresiama Velikkakam, Fernanda Villani, Janete Soares Coelho, Claudia Ida Brodskyn, Andrea Teixeira, Kenneth J. Gollob, Maria do Carmo P. Nunes, Walderez O. Dutra
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.787423/full