Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan® products through human skin

Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan® products through human skin

In the treatment of pain, especially chronic pain, the rule of multimodal therapy applies, based on various painkillers mechanisms of action. The aim of the conducted study was to evaluate the in vitro penetration of ketoprofen (KET) and lidocaine hydrochloride (LH) through the human skin from a veh...

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Bibliographic Details
Main Authors: Urszula Adamiak-Giera, Anna Nowak, Wiktoria Duchnik, Paula Ossowicz-Rupniewska, Anna Czerkawska, Anna Machoy-Mokrzyńska, Tadeusz Sulikowski, Łukasz Kucharski, Marta Białecka, Adam Klimowicz, Monika Białecka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
penetration skin
vehicles
ketoprofen
lidocaine hydrochloride
Franz diffusion cell
human skin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1157977/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1157977/full

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