Complement Protein C3 Suppresses Axon Growth and Promotes Neuron Loss

Abstract The inflammatory response to spinal cord injury (SCI) involves localization and activation of innate and adaptive immune cells and proteins, including the complement cascade. Complement C3 is important for the classical, alternative, and lectin pathways of complement activation, and its cle...

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Bibliographic Details
Main Authors: Sheri L. Peterson, Hal X. Nguyen, Oscar A. Mendez, Aileen J. Anderson
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-11410-x