Complement Protein C3 Suppresses Axon Growth and Promotes Neuron Loss
Abstract The inflammatory response to spinal cord injury (SCI) involves localization and activation of innate and adaptive immune cells and proteins, including the complement cascade. Complement C3 is important for the classical, alternative, and lectin pathways of complement activation, and its cle...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-11410-x |