A method for the generation of ectromelia virus (ECTV) recombinants: in vivo analysis of ECTV vCD30 deletion mutants.

Ectromelia virus (ECTV) is the causative agent of mousepox, a lethal disease of mice with similarities to human smallpox. Mousepox progression involves replication at the initial site of infection, usually the skin, followed by a rapid spread to the secondary replicative organs, spleen and liver, an...

Full description

Bibliographic Details
Main Authors: Ali Alejo, Margarida Saraiva, Maria Begoña Ruiz-Argüello, Abel Viejo-Borbolla, Mar Fernández de Marco, Francisco Javier Salguero, Antonio Alcami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2664468?pdf=render